Vancomycin-associated drug-induced hypersensitivity syndrome

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A case of vancomycin-induced drug hypersensitivity syndrome

The drug hypersensitivity syndrome (DHS) is a severe, idiosyncratic multi-system reaction caused by drugs. It is defined by the clinical triad of fever, rash and internal organ involvement 1) . Vancomycin has rarely been reported as a cause of the DHS 2) . There are only a few cases of suspected DHS due to vancomycin previously reported in the medical literature 3-5) . In 1990, Hannah et al. 3)...

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Drug-induced hypersensitivity syndrome induced by clindamycin.

© 2013 The Authors. doi: 10.2340/00015555-1363 Journal Compilation © 2013 Acta Dermato-Venereologica. ISSN 0001-5555 Drug-induced hypersensitivity syndrome (DIHS), also known as drug rash with eosinophilia and systemic symptoms (DRESS), is a severe, adverse drug reaction characterized by skin rash, fever, lymphadenopathy, hepatitis and haematological abnormalities (1, 2). The presence of human ...

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Monomyeloid precursors in drug-induced hypersensitivity syndrome

Drug-induced hypersensitivity syndrome (DIHS), also known as drug reactions with eosinophila and systemic symptoms, has unique clinical features including fever, generalized rash, lymphadenopathy and extracutaneous organ involvements. During the disease course, human herpesvirus (HHV)-6 reactivation is frequently (60%<) observed in association with unfavorable outcomes. We recently noticed a tr...

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Drug induced hypersensitivity syndrome has been reported to a variety of drugs. Reactivation of herpes viruses is associated with relapse of symptoms even as late as five weeks after stopping the inciting drug. We report here a case of drug hypersensitivity with CMV reactivation which was treated successfully.

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ژورنال

عنوان ژورنال: Journal of the American Academy of Dermatology

سال: 2019

ISSN: 0190-9622

DOI: 10.1016/j.jaad.2019.02.002